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1

Design, synthesis and molecular modeling studies on novel moxifloxacin derivatives as potential antibacterial and antituberculosis agents

Türe, Aslı, Kulabaş, Necla, İpek Dingiş, Serap, Birgül, Kaan, Bozdeveci, Arif, Alpay Karaoğlu, Şengül, Siva Krishna, Vagolu, Sriram, Dharmarajan, Küçükgüzel, İlkay

Journal:

Bioorganic Chemistry

Year:

2019

Language:

english

File:

PDF, 2.46 MB

english, 2019

2

Synthesis of some novel thiourea derivatives obtained from 5-[(4-aminophenoxy)methyl]-4-alkyl/aryl-2,4-dihydro-3H-1,2,4-triazole-3-thiones and evaluation as antiviral/anti-HIV and anti-tuberculosis agents

İlkay Küçükgüzel, Esra Tatar, Ş. Güniz Küçükgüzel, Sevim Rollas, Erik De Clercq

Journal:

European Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 394 KB

english, 2008

3

A rapid, sensitive high performance liquid chromatographic method for the determination of meropenem in pharmaceutical dosage form, human serum and urine

Yalcin Özkan, İlkay Küçükgüzel, Sibel A. Özkan, Hassan Y. Aboul-Enein

Journal:

Biomedical Chromatography

Year:

2001

Language:

english

File:

PDF, 96 KB

english, 2001

4

Synthesis of some novel heterocyclic compounds derived from diflunisal hydrazide as potential anti-infective and anti-inflammatory agents

Ş. Güniz Küçükgüzel, İlkay Küçükgüzel, Esra Tatar, Sevim Rollas, Fikrettin Şahin, Medine Güllüce, Erik De Clercq, Levent Kabasakal

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 359 KB

english, 2007

5

Development and validation of a rapid RP-HPLC method for the determination of cetirizine or fexofenadine with pseudoephedrine in binary pharmaceutical dosage forms

Sevgi Karakuş, İlkay Küçükgüzel, Ş.Güniz Küçükgüzel

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2008

Language:

english

File:

PDF, 477 KB

english, 2008

6

Synthesis and antimycobacterial activity of some coupling products from 4-aminobenzoic acid hydrazones

Ş.Güniz Küçükgüzel, Sevim Rollas, Ilkay Küçükgüzel, Muammer Kiraz

Journal:

European Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 83 KB

english, 1999

7

Some 3-Thioxo/alkylthio-1,2,4-triazoles with a substituted thiourea moiety as possible antimycobacterials

Ilkay Küçükgüzel, S.Güniz Küçükgüzel, Sevim Rollas, Muammer Kiraz

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 153 KB

english, 2001

8

Detection of nimesulide metabolites in rat plasma and hepatic subcellular fractions by HPLC-UV/DAD and LC-MS/MS studies

Ş. Güniz Küçükgüzel, İlkay Küçükgüzel, Başak Oral, Sena Sezen, Sevİm Rollas

Journal:

European Journal of Drug Metabolism and Pharmacokinetics

Year:

2005

Language:

english

File:

PDF, 825 KB

english, 2005

9

Synthesis, antiviral and anticancer activity of some novel thioureas derivedfrom N-(4-nitro-2-phenoxyphenyl)-methanesulfonamide

Sevgi Karakuş, Ş. Güniz Küçükgüzel, İlkay Küçükgüzel, Erik De Clercq, Christophe Pannecouque, Graciela Andrei, Robert Snoeck, Fikrettin Şahin, Ömer Faruk Bayrak

Journal:

European Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 202 KB

english, 2009

10

Synthesis of some 3-(Arylalkylthio)-4-alkyl/aryl-5-(4-aminophenyl)-4H-1,2,4-triazole derivatives and their anticonvulsant activity

İlkay Küçükgüzel, Ş. Güniz Küçükgüzel, Sevim Rollas, Gülten Ötük-Sanış, Osman Özdemir, İbrahim Bayrak, Tuncay Altuğ, James P. Stables

Journal:

Year:

2004

Language:

english

File:

PDF, 297 KB

english, 2004

11

Metabolic and chemical studies on N-(4-chlorobenzyl)-N′-benzoylhydrazine

Ş.Güniz Küçükgüzel, İlkay Küçükgüzel, Mert Ülgen

Journal:

Year:

2000

Language:

english

File:

PDF, 139 KB

english, 2000

12

In vitro hepatic microsomal metabolism of N-benzyl-N-methylaniline

Ilkay Küçükgüzel, Mert Ülgen, John W Gorrod

Journal:

Year:

1999

Language:

english

File:

PDF, 203 KB

english, 1999

13

Some Hydrazones of 2-Aroylamino-3-methylbutanohydrazide: Synthesis, Molecular Modeling Studies, and Identification as Stereoselective Inhibitors of HIV-1

Tatar, Esra, Küçükgüzel, İlkay, Daelemans, Dirk, Talele, Tanaji T., Kaushik-Basu, Neerja, De Clercq, Erik, Pannecouque, Christophe

Journal:

Archiv der Pharmazie

Year:

2013

Language:

english

File:

PDF, 358 KB

english, 2013

14

Synthesis and characterization of flurbiprofen hydrazide derivatives as potential anti-HCV, anticancer and antimicrobial agents

Pelin Çıkla, Esra Tatar, İlkay Küçükgüzel, Fikrettin Şahin…

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 643 KB

english, 2013

15

2-Heteroarylimino-5-arylidene-4-thiazolidinones as a new class of non-nucleoside inhibitors of HCV NS5B polymerase

Küçükgüzel, İlkay, Satılmış, Gökhan, Gurukumar, K.R., Basu, Amartya, Tatar, Esra, Nichols, Daniel B., Talele, Tanaji T., Kaushik-Basu, Neerja

Journal:

European Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 846 KB

english, 2013

16

Novel 4-Thiazolidinones as Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B RNA-Dependent RNA Polymerase

Çakır, Gizem, Küçükgüzel, İlkay, Guhamazumder, Rupa, Tatar, Esra, Manvar, Dinesh, Basu, Amartya, Patel, Bhargav A., Zia, Javairia, Talele, Tanaji T., Kaushik-Basu, Neerja

Journal:

Archiv der Pharmazie

Year:

2015

Language:

english

File:

PDF, 881 KB

english, 2015

17

Synthesis and Characterization of Certain Thiourea Derivatives Starting from 1,2,4-Triazoline-3-Thiones as Potential Antibacterial and Antifungal Agents

Küçükgüzel, İlkay, Rollas, Sevim, Çevikbaş, Adile

Journal:

Drug Metabolism and Drug Interactions

Year:

1995

Language:

english

File:

PDF, 1.00 MB

english, 1995

18

MICROSOMAL METABOLISM OF N-BENZYL-N-ETHYLANILINE AND N-BENZYL-N-ETHYL-p-TOLUIDINE

Ulgen, Mert, Ozer, Ufuk, Kucukguzel, Ilkay, Gorrod, John W.

Journal:

Drug Metabolism and Drug Interactions

Year:

1997

Language:

english

File:

PDF, 1.70 MB

english, 1997

19

Discovery of conjugated thiazolidinone-thiadiazole scaffold as anti-dengue virus polymerase inhibitors

Manvar, Dinesh, Küçükgüzel, İlkay, Erensoy, Gizem, Tatar, Esra, Deryabaşoğulları, Gökhan, Reddy, Haarika, Talele, Tanaji T., Cevik, Ozge, Kaushik-Basu, Neerja

Journal:

Biochemical and Biophysical Research Communications

Year:

2015

Language:

english

File:

PDF, 839 KB

english, 2015

20

Synthesis and antiproliferative evaluation of novel 2-(4H-1,2,4-triazole-3-ylthio)acetamide derivatives as inducers of apoptosis in cancer cells

Kulabaş, Necla, Tatar, Esra, Bingöl Özakpınar, Özlem, Özsavcı, Derya, Pannecouque, Christophe, De Clercq, Erik, Küçükgüzel, İlkay

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.98 MB

english, 2016

21

The Structure - Antituberculosis Activity Relationships Study in a Series of 5-(4-Aminophenyl)-4-Substituted-2,4-Dihydro-3h-1,2,4-Triazole-3-Thione Derivatives. A Combined Electronic-Topological and Neural Networks Approach

Kandemirli, Fatma, Shvets, Nathali, Unsalan, Seda, Kucukguzel, Ilkay, Rollas, Sevim, Kovalishyn, Vasyl, Dimoglo, Anatholy

Journal:

Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 234 KB

english, 2006

22

Three-dimensional structure syn / anti isomers of a valin hydrazone

Cela, Dorisa, Nepravishta, Ridvan, Mandaliti, Walter, Tatar, Esra, Şenkardeş, Sevil, Küçükgüzel, İlkay, Küçükgüzel, Ş. Güniz, Paci, Maurizio

Journal:

Acta Crystallographica Section A Foundations and Advances

Year:

2017

Language:

english

File:

PDF, 45 KB

english, 2017

23

Synthesis, anticancer activity, toxicity evaluation and molecular docking studies of novel phenylaminopyrimidine—(thio)urea hybrids as potential kinase inhibitors

Türe, Aslı, Kahraman, Deniz Cansen, Cetin-Atalay, Rengul, Helvacıoğlu, Sinem, Charehsaz, Mohammad, Küçükgüzel, İlkay

Journal:

Computational Biology and Chemistry

Year:

2018

Language:

english

File:

PDF, 770 KB

english, 2018

24

Synthesis, molecular docking and evaluation of novel sulfonyl hydrazones as anticancer agents and COX-2 inhibitors

Şenkardeş, Sevil, Han, M. İhsan, Kulabaş, Necla, Abbak, Mürüvvet, Çevik, Özge, Küçükgüzel, İlkay, Küçükgüzel, Ş. Güniz

Journal:

Molecular Diversity

Year:

2019

Language:

english

File:

PDF, 2.55 MB

english, 2019

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